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Glucose 6 phosphate isomerase Recombinant Rabbit Monoclonal Antibody [JG33-86] (ET7108-01)

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Catalog# ET7108-01

Rabbit Monoclonal to Glucose 6 phosphate isomerase

Tested for

  • WB

  • IHC-P

  • FC

  • IF-Cell

  • IF-Tissue

Reacts with

  • Human

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Glucose 6 phosphate isomerase Recombinant Rabbit Monoclonal Antibody [JG33-86] (ET7108-01)

Immunogen

Recombinant protein within human glucose 6 phosphate isomerase aa 1-128 / 558.

Host

Rabbit

Positive Control

A549 cell lysates, HepG2 cell lysates, LO2, MCF-7, human colon tissue, human prostate tissue, human kidney tissue, A549.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JG33-86

RRID

AB_3070804

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IF-Cell

  • 1:50-1:200

  • IF-Tissue

  • 1:50-1:200

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 63 kDa

Isotype

IgG

TARGET

UNIPROT #

P06744

PROTEIN NAME

Glucose 6 phosphate isomerase

SYNONYMS

AMF antibody;Aurocrine motility factor antibody;Autocrine motility factor antibody;DKFZp686C13233 antibody;EC 5.3.1.9 antibody;G6PI_HUMAN antibody;Glucose phosphate isomerase antibody;Glucose-6-phosphate isomerase antibody;GNPI antibody;GPI antibody;Gpi1 antibody;Hexose monophosphate isomerase antibody;Hexosephosphate isomerase antibody;Neuroleukin antibody;NLK antibody;Oxoisomerase antibody;PGI antibody;PHI antibody;Phosphoglucose isomerase antibody;Phosphohexomutase antibody;Phosphohexose isomerase antibody;Phosphosaccharomutase antibody;SA 36 antibody;SA-36 antibody;SA36 antibody

SEQUENCE SIMILARITIES

Belongs to the GPI family.

POST-TRANSLATIONAL MODIFICATION

Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.; ISGylated.

SUBCELLULAR LOCATION

Cytoplasm. Secreted.

FUNCTION

Glucose-6-phosphate isomerase (GPI) has many other names, including Phosphohexose isomerase (PHI), Neuroleukin (NLK) and Spermantigen-36 (SA-36). GPI is a cytoplasmic homodimer belonging to the GPI family. It is a neurotrophic factor for spinal and sensory neurons and is involved in glycolysis and gluconeogenesis. Defects or mutations in GPI can cause hereditary nonspherocytic hemolytic anemia (HA), hydrops fetalis, immediate neonatal death and neurological impairment.

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