GFAP Rabbit Polyclonal Antibody (R1308-10)
Catalog# R1308-10
Rabbit Polyclonal to GFAP
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WB
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IF-Cell
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IHC-P
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Human
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Mouse
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Rat
Specifications
Product Type
Rabbit polyclonal primary
Product Name
GFAP Rabbit Polyclonal Antibody (R1308-10)
Immunogen
Synthetic peptide within c-terminal residues of gfap.
Host
Rabbit
Positive Control
Human brain, A172, mouse brain tissue lysate, rat brain tissue lysate.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:5,000-1:10,000
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IF-Cell
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1:50-1:100
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IHC-P
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1:200
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 50 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
GFAP
SYNONYMS
wu:fb34h11 antibody;ALXDRD antibody;cb345 antibody;etID36982.3 antibody;FLJ42474 antibody;FLJ45472 antibody;GFAP antibody;GFAP_HUMAN antibody;gfapl antibody;Glial fibrillary acidic protein antibody;Intermediate filament protein antibody;wu:fk42c12 antibody;xx:af506734 antibody;zgc:110485 antibody
SEQUENCE SIMILARITIES
Belongs to the intermediate filament family.
TISSUE SPECIFICITY
Expressed in cells lacking fibronectin.
POST-TRANSLATIONAL MODIFICATION
Phosphorylated by PKN1.
SUBCELLULAR LOCATION
Cytoplasm, Intermediate filament.
FUNCTION
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. In particular, vimentin filaments are present at early developmental stages, while GFAP filaments are characteristic of differentiated and mature brain astrocytes. In addition, GFAP intermediate filaments are also present in nonmyelin-forming Schwann cells in the peripheral nervous system.
CITATIONS
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Xudong Pan,et al
Lnc_011797 promotes ferroptosis and aggravates white matter lesions
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IHC
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Human
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Citation
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