Lane 1: Hela cell lysate
Lane 2: human skin tissue lysate
Recombinant Rabbit monoclonal primary
gamma Catenin Recombinant Rabbit Monoclonal Antibody [JF0973] (ET1702-33)
Hela cell lysate, human skin tissue lysate, Hela, MCF-7, A431, mouse stomach tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
ARVD 12 antibody; ARVD12 antibody; Catenin (cadherin associated protein), gamma 80kDa antibody; catenin (cadherin-associated protein) gamma (80kD) antibody; Catenin gamma antibody; CTNNG antibody; Desmoplakin 3 antibody; Desmoplakin III antibody; Desmoplakin-3 antibody; Desmoplakin3 antibody; DesmoplakinIII antibody; DP 3 antibody; DP III antibody; DP3 antibody; DPIII antibody; gamma catenin antibody; Junction plakoglobin antibody; JUP antibody; OTTHUMP00000164732 antibody; OTTHUMP00000164735 antibody; OTTHUMP00000164738 antibody; PDGB antibody; PKGB antibody; PLAK_HUMAN antibody; PLAKOGLOBIN antibody
Belongs to the beta-catenin family.
May be phosphorylated by FER.
Cytoskeleton, adherens junction, desmosome, Membrane.
The catenins, α, β and γ, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, binds with α-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTP? associates with catenin/cadherin complexes and may regulate complex signaling.