PRODUCT CODE: ET7107-54

Galectin 7 Recombinant Rabbit Monoclonal Antibody [JB38-11] (ET7107-54)

  • Recombinant

Applications

  • WB

  • ICC

  • IF

  • IHC-P

  • IP

REACTIVITY

  • Human

Western blot analysis of Galectin 7 on human skin tissue lysate using anti-Galectin 7 antibody at 1/500 dilution.
  • Western blot analysis of Galectin 7 on human skin tissue lysate using anti-Galectin 7 antibody at 1/500 dilution.
  • ICC staining Galectin 7 in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • ICC staining Galectin 7 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Galectin 7 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human skin tissue using anti-Galectin 7 antibody. Counter stained with hematoxylin.
Western blot analysis of Galectin 7 on human skin tissue lysate using anti-Galectin 7 antibody at 1/500 dilution.

Applications

  • WB

  • ICC

  • IF

  • IHC-P

  • IP

REACTIVITY

  • Human

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Galectin 7 Recombinant Rabbit Monoclonal Antibody [JB38-11] (ET7107-54)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

A431, HUVEC, human skin tissue, human tonsil tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JB38-11

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

15 kDa

Isotype

IgG

APPLICATION DILUTION

  • ICC

  • 1:50-1:200

  • IHC-P

  • 1:100-1:300

  • WB

  • 1:500-1:1,000

  • IP

  • 1:10-1:50

TARGET

UNIPROT #

PROTEIN NAME

Galectin 7

SYNONYMS

Gal-7 antibody; GAL7 antibody; Galectin 7B antibody; Galectin-7 antibody; HKL-14 antibody; Human keratinocyte lectin 14 antibody; Keratinocyte lectin 14 antibody; Lectin galactoside binding soluble 7 antibody; Lectin, galactoside binding, soluble, 7B antibody; LEG7_HUMAN antibody; LGALS7 antibody; LGALS7A antibody; LGALS7B antibody; P53 induced protein 1 antibody; p53-induced gene 1 protein antibody; Pi7 antibody; PIG1 antibody; TP53I1 antibody

TISSUE SPECIFICITY

Mainly expressed in stratified squamous epithelium.

SUBCELLULAR LOCATION

Cytoplasm. Nucleus. Secreted.

FUNCTION

Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Galectin-7, expressed mainly in stratified squamous epithelium, is activated by p53 and repressed by retinoic acid. It is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release. The galectin-7 gene maps to chromosome 19. Mainly expressed in stratified squamous epithelium.