Recombinant Rabbit monoclonal primary
Galectin 1 Recombinant Rabbit Monoclonal Antibody [JM13-37] (ET1705-83)
Human skeletal muscle tissue lysates, A431, rat stomach tissue, human placenta tissue, NIH/3T3.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
14 kDa laminin-binding protein antibody; 14 kDa lectin antibody; Beta galactoside binding lectin antibody; Beta galactoside binding lectin L 14 I antibody; beta galactoside binding protein antibody; Beta-galactoside-binding lectin L-14-I antibody; DKFZp686E23103 antibody; Gal 1 antibody; Gal-1 antibody; GAL1 antibody; Galaptin antibody; Galbp antibody; Galectin antibody; Galectin-1 antibody; Galectin1 antibody; GBP antibody; HBL antibody; HLBP14 antibody; HPL antibody; L 14.5 antibody; L-14.5 antibody; L14 antibody; Lactose binding lectin 1 antibody; Lactose-binding lectin 1 antibody; Lect14 antibody; Lectin galactoside binding soluble 1 antibody; Lectin galactoside-binding soluble 1 antibody; LEG1_HUMAN antibody; LGALS 1 antibody; LGALS1 antibody; Lgals1 lectin galactose binding soluble 1 antibody; MAPK activating protein MP12 antibody; Putative MAPK activating protein MP12 antibody; Putative MAPK-activating protein PM12 antibody; S Lac lectin 1 antibody; S-Lac lectin 1 antibody
Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Specifically, Galectin-1 is an autocrine regulator of cell-proliferation that plays a role in the maintenance of G0 and in the control of G2 traverse. Galectin-1, also known as LGALS1, is the protein product of a single gene linked to human chromosome 22q13.1. The Galectin-1 protein contains 135 amino acids, a single internal EcoRI site and a polyadenylation signal. Galectin-1 can localize to both intracellular and extracellular space. Galectin-1 is expressed in human placenta, human lung, HL-6, HepG2 and CEM cells.