GABPA Rabbit Polyclonal Antibody (HA500187)

UNIPROT #

Q06546

PROTEIN NAME

GABPA

SYNONYMS

E4TF 1A antibody;E4TF1 60 antibody;E4TF1A antibody;GA binding protein alpha chain antibody;GA binding protein transcription factor alpha subunit 60kDa antibody;GA binding protein transcription factor alpha subunit antibody;GA-binding protein alpha chain antibody;GABP A antibody;GABP alpha subunit antibody;GABP subunit alpha antibody;Gabpa antibody;GABPA_HUMAN antibody;Human nuclear respiratory factor 2 subunit alpha antibody;NFT 2 antibody;NFT2 antibody;NRF 2 antibody;NRF 2A antibody;NRF2 antibody;NRF2A antibody;Nuclear respiratory factor 2 alpha subunit antibody;Nuclear respiratory factor 2 subunit alpha antibody;RCH04A07 antibody;Transcription factor E4TF1 60 antibody;Transcription factor E4TF1-60 antibody

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.