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FOXP3 Rabbit Polyclonal Antibody (IRS147RB)

Price: Regular price $278.00

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Catalog# IRS147RB

Rabbit Polyclonal to FOXP3

Tested for

  • mIHC

Reacts with

  • Mouse

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

FOXP3 Rabbit Polyclonal Antibody (IRS147RB)

Immunogen

Klh conjugated synthetic peptide.

Host

Rabbit

Positive Control

Mouse spleen tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Purification

Affinity purification

Molecular Weight

Predicted band size: 47 kDa

Isotype

IgG

TARGET

UNIPROT #

Q99JB6

PROTEIN NAME

FOXP3

SYNONYMS

AIID antibody;DIETER antibody;Forkhead box P3 antibody;Forkhead box protein P3 antibody;FOXP3 antibody;FOXP3_HUMAN antibody;FOXP3delta7 antibody;Immune dysregulation polyendocrinopathy enteropathy X linked antibody;Immunodeficiency polyendocrinopathy enteropathy X linked antibody;IPEX antibody;JM2 antibody;MGC141961 antibody;MGC141963 antibody;OTTHUMP00000025832 antibody;OTTHUMP00000025833 antibody;OTTHUMP00000226737 antibody;PIDX antibody;Scurfin antibody;XPID antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

FOXP3 (forkhead box P3), also known as scurfin, is a protein involved in immune system responses. A member of the FOX protein family, FOXP3 appears to function as a master regulator of the regulatory pathway in the development and function of regulatory T cells. Regulatory T cells generally turn the immune response down. In cancer, an excess of regulatory T cell activity can prevent the immune system from destroying cancer cells. In autoimmune disease, a deficiency of regulatory T cell activity can allow other autoimmune cells to attack the body's own tissues.

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