Applications
-
WB
-
IHC-P
-
ICC
-
FC
REACTIVITY
-
Human
-
Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
Follistatin Rabbit Polyclonal Antibody (ER1901-69)
Immunogen
Recombinant protein within human follistatin aa 11-216 / 344.
Host
Rabbit
Positive Control
Rat colon tissue lysates, Raji cell lysates, Hela, MCF-7, human placenta tissue, HepG2.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein affinity purified.
MOLECULAR WEIGHT
Predicted band size 38 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:2000
-
IHC-P
-
1:50-1:200
-
ICC
-
1:50-1:200
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
Follistatin
SYNONYMS
FS,Activin-binding protein,fst
TISSUE SPECIFICITY
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
SUBCELLULAR LOCATION
Secreted.
FUNCTION
Follistatin also known as activin-binding protein is a protein that in humans is encoded by the FST gene. Follistatin is an autocrine glycoprotein that is expressed in nearly all tissues of higher animals. Its primary function is the binding and bioneutralization of members of the TGF-β superfamily, with a particular focus on activin, a paracrine hormone.Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).