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FAM13C1 Rabbit Polyclonal Antibody (HA500122)

Price: Regular price $315.00

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Catalog# HA500122

Rabbit Polyclonal to FAM13C1

Tested for

  • WB

  • IHC-P

Reacts with

  • Human

  • Mouse

  • Rat

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Specifications

Product Type

Rabbit polyclonal primary

Product Name

FAM13C1 Rabbit Polyclonal Antibody (HA500122)

Immunogen

Synthetic peptide within human fam13c1 aa 241-270.

Host

Rabbit

Positive Control

HepG2 cell lysate, Rat brain tissue lysate, human colon tissue, mouse colon tissue, rat colon tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

RRID

AB_3071220

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:1,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Immunogen affinity purified.

Molecular Weight

Predicted band size: 66 kDa

Isotype

IgG

TARGET

UNIPROT #

Q8NE31

PROTEIN NAME

FAM13C1

SYNONYMS

Protein FAM13C;FAM13C;FAM13C1

FUNCTION

FAM13C1 (family with sequence similarity 13, member C), also known as FAM13C, is a 585 amino acid protein that belongs to the FAM13 family. Existing as three alternatively spliced isoforms, the gene encoding FAM13C1 maps to human chromosome 10, which contains over 800 genes, 135 million nucleotides and makes up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.

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