Factor IX Rabbit Polyclonal Antibody (HA500035)

UNIPROT #

P00740

PROTEIN NAME

Factor IX

SYNONYMS

Christmas Disease antibody;Christmas factor antibody;Coagulant factor IX antibody;Coagulation factor 9 antibody;Coagulation factor IX antibody;Coagulation factor IXa heavy chain antibody;F9 antibody;FA9_HUMAN antibody;Factor 9 antibody;Factor IX Deficiency antibody;FactorIX antibody;FIX antibody;Haemophilia B antibody;HEMB antibody;MGC129641 antibody;MGC129642 antibody;P19 antibody;Plasma Thromboplastic Component antibody;Plasma thromboplastin component antibody;PTC antibody

SUBCELLULAR LOCATION

Secreted.

FUNCTION

Factor IX (or Christmas factor) (EC 3.4.21.22) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1. Deficiency of this protein causes haemophilia B. It was discovered in 1952 after a young boy named Stephen Christmas was found to be lacking this exact factor, leading to haemophilia.Factor IX complex is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system.The gene for factor IX is located on the X chromosome (Xq27.1-q27.2) and is therefore X-linked recessive: mutations in this gene affect males much more frequently than females.