Applications
-
WB
-
IHC-P
-
FC
-
ICC
-
IF
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Recombinant Rabbit monoclonal primary
Product Name
Exportin-5 Recombinant Rabbit Monoclonal Antibody [JE40-91] (ET7109-18)
Immunogen
Recombinant protein within human exportin-5 aa 1-200.
Host
Rabbit
Positive Control
293, rat epididymis tissue, human lung cancer tissue, human thyroid gland tissue, human breast tissue, mouse testis tissue, K562.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JE40-91
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein A purified.
MOLECULAR WEIGHT
136 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:2,000
-
IHC-P
-
1:100-1:400
-
FC
-
1:50-1:100
-
ICC/IF
-
1:100
TARGET
UNIPROT #
PROTEIN NAME
Exportin-5
SYNONYMS
Exp 5 antibody; Exp5 antibody; Exportin 5 antibody; Exportin-5 antibody; Exportin5 antibody; FLJ14239 antibody; FLJ32057 antibody; FLJ45606 antibody; KIAA1291 antibody; OTTHUMP00000016472 antibody; Ran binding protein 21 antibody; Ran-binding protein 21 antibody; Ranbp 21 antibody; Ranbp21 antibody; Xpo 5 antibody; xpo5 antibody; XPO5_HUMAN antibody
SEQUENCE SIMILARITIES
Belongs to the exportin family.
TISSUE SPECIFICITY
Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.
SUBCELLULAR LOCATION
Cytoplasm. Nucleus.
FUNCTION
The karyopherin-related nuclear transport factor Exportin 5, also known as Exp5, preferentially recognizes and transports RNAs containing minihelix motifs, structural cis-acting export elements that comprise a double-stranded stem (14 nucleotides) with a base-paired 5' end and a 3-8-nucleotide protruding 3' end. Exportin 5 also mediates protein transport between the nuclear and cytoplasmic compartment. Exportin 5 belongs to a large family of karyopherins and stimulates nuclear export of dsRNA binding proteins eEF1A and tRNA.