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Exportin-5 Recombinant Rabbit Monoclonal Antibody [JE40-91] (ET7109-18)

Price: Regular price $355.00

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Catalog# ET7109-18

Rabbit Monoclonal to Exportin-5

Tested for

  • WB

  • IHC-P

  • FC

  • ICC/IF

React with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Exportin-5 Recombinant Rabbit Monoclonal Antibody [JE40-91] (ET7109-18)

Immunogen

Recombinant protein within human exportin-5 aa 1-240 / 1,204.

Host

Rabbit

Positive Control

293, rat epididymis tissue, human lung cancer tissue, human thyroid gland tissue, human breast tissue, mouse testis tissue, K562.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JE40-91

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:100-1:400

  • FC

  • 1:50-1:100

  • ICC/IF

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

136 kDa

Isotype

IgG

TARGET

UNIPROT #

Q9HAV4

PROTEIN NAME

Exportin-5

SYNONYMS

Exp 5 antibody;Exp5 antibody;Exportin 5 antibody;Exportin-5 antibody;Exportin5 antibody;FLJ14239 antibody;FLJ32057 antibody;FLJ45606 antibody;KIAA1291 antibody;OTTHUMP00000016472 antibody;Ran binding protein 21 antibody;Ran-binding protein 21 antibody;Ranbp 21 antibody;Ranbp21 antibody;Xpo 5 antibody;xpo5 antibody;XPO5_HUMAN antibody

SEQUENCE SIMILARITIES

Belongs to the exportin family.

TISSUE SPECIFICITY

Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

SUBCELLULAR LOCATION

Cytoplasm. Nucleus.

FUNCTION

The karyopherin-related nuclear transport factor Exportin 5, also known as Exp5, preferentially recognizes and transports RNAs containing minihelix motifs, structural cis-acting export elements that comprise a double-stranded stem (14 nucleotides) with a base-paired 5' end and a 3-8-nucleotide protruding 3' end. Exportin 5 also mediates protein transport between the nuclear and cytoplasmic compartment. Exportin 5 belongs to a large family of karyopherins and stimulates nuclear export of dsRNA binding proteins eEF1A and tRNA.

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