Lane 1: Hela cell lysate, untreated
Lane 2: MCF-7 cell lysate, untreated
Lane 3: HepG2 cell lysate, untreated
Lane 4: PANC-1 cell lysate, untreated
Lane 5: PC-12 cell lysate, untreated
Lane 6: Human liver tissue lysate, untreated
Rabbit polyclonal primary
ERp72 Rabbit Polyclonal Antibody (R1409-1)
Synthetic peptide of the c-terminal residues of human erp72.
Hela, MCF-7, HepG2, PANC-1, PC-12, human liver tissue, A549, human lung cancer tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Calcium binding protein intestinal related antibody; Endoplasmic reticulum resident protein 70 antibody; Endoplasmic reticulum resident protein 72 antibody; EPR70 antibody; EPR72 antibody; ER protein 70 antibody; ER protein 72 antibody; ERP 70 antibody; ERp 72 antibody; ERp-72 antibody; ERp70 antibody; ERp72 antibody; PDIA 4 antibody; Pdia4 antibody; PDIA4_HUMAN antibody; PDIR antibody; Protein disulfide isomerase A4 antibody; Protein disulfide isomerase associated 4 antibody; Protein disulfide isomerase family A member 4 antibody; protein disulfide isomerase related protein (calcium-binding protein, intestinal-related) antibody; Protein disulfide isomerase related protein antibody; Protein disulfide-isomerase A4 antibody; Protein ERp 72 antibody; Protein ERp72 antibody
Belongs to the protein disulfide isomerase family.
Protein disulfide isomerase or PDI is an enzyme in the endoplasmic reticulum in eukaryotes that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. PDI contains four thioredoxin-like domains, two of which retain the canonical CXXC motif. The reduced (that is, dithiol) form of PDI is able to catalyse a reduction of mispaired thiol residues of a particular substrate, acting as an isomerase. Another major function of PDI relates to its activity as a chaperone; i.e., it aids wrongly folded proteins to reach a correctly folded state without the aid of enzymatic disulfide shuffling. PDI helps load antigenic peptides into MHC class I molecules. These molecules (MHC I) are related to the peptide presentation by antigen-presenting cells in the immune response.