Eph receptor B2 Recombinant Rabbit Monoclonal Antibody [PSH14-91] (HA723693)

UNIPROT #

P29323

PROTEIN NAME

Eph receptor B2

SYNONYMS

cek5 antibody;Developmentally regulated EPH related tyrosine kinase antibody;DRT antibody;EK5 antibody;ELK related protein tyrosine kinase antibody;Eph receptor B2 antibody;EPH tyrosine kinase 3 antibody;EPH-like kinase 5 antibody;EPHB2 antibody;EPHB2_HUMAN antibody;Ephrin type B receptor 2 antibody;Ephrin type-B receptor 2 antibody;EPHT 3 antibody;ERK antibody;ETECK antibody;hEK5 antibody;Nuk antibody;Prkm 5 antibody;Receptor protein tyrosine kinase HEK 5 antibody;Renal carcinoma antigen NY-REN-47 antibody;Sek 3 antibody;Tyro 5 antibody;Tyrosine protein kinase receptor CEK 5 antibody;Tyrosine protein kinase receptor EPH 3 antibody;Tyrosine protein kinase receptor QEK 5 antibody;Tyrosine-protein kinase receptor EPH-3 antibody;Tyrosine-protein kinase TYRO5 antibody

SUBCELLULAR LOCATION

Cell membrane, Cell projection, axon, , dendrite.

FUNCTION

Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.