Eph receptor B1 Recombinant Rabbit Monoclonal Antibody [JE39-46] (HA722345)

UNIPROT #

P54762

PROTEIN NAME

Eph receptor B1

SYNONYMS

Cek 6 antibody;EK6 antibody;ELK antibody;Elkh antibody;EPH receptor B1 antibody;Eph tyrosine kinase 2 antibody;EPH-like kinase 6 antibody;Ephb1 antibody;EPHB1_HUMAN antibody;Ephrin type B receptor 1 antibody;Ephrin type-B receptor 1 antibody;EPHT2 antibody;HEK 6 antibody;HEK6 antibody;NET antibody;Neuronally-expressed EPH-related tyrosine kinase antibody;soluble EPHB1 variant 1 antibody;Tyrosine protein kinase receptor EPH 2 antibody;Tyrosine-protein kinase receptor EPH-2 antibody

SUBCELLULAR LOCATION

Cell membrane, Early endosome membrane, Cell projection, dendrite.

FUNCTION

Ephrin type-B receptor 1 is a protein that in humans is encoded by the EPHB1 gene. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.