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EpCAM Recombinant Rabbit Monoclonal Antibody (IRS254RB)

Price: Regular price $278.00

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Catalog# IRS254RB

Rabbit Monoclonal to EpCAM

Tested for

  • mIHC

Reacts with

  • Human

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

EpCAM Recombinant Rabbit Monoclonal Antibody (IRS254RB)

Host

Rabbit

Positive Control

Human colon tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

APPLICATION DILUTION

  • mIHC

  • 1:100

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 35 kDa

Isotype

IgG

TARGET

UNIPROT #

P16422

PROTEIN NAME

EpCAM

SYNONYMS

17 1A antibody;323/A3 antibody;Adenocarcinoma associated antigen antibody;Adenocarcinoma-associated antigen antibody;Antigen identified by monoclonal antibody;AUA1 antibody;AUA1 antibody;CD326 antibody;CD326 antigen antibody;Cell surface glycoprotein Trop 1 antibody;Cell surface glycoprotein Trop 2 antibody;Cell surface glycoprotein Trop-1 antibody;CO 17A antibody;CO17 1A antibody;CO17A antibody;DIAR5 antibody;EGP 2 antibody;EGP antibody;EGP2 antibody;EGP314 antibody;EGP40 antibody;Ep CAM antibody;Ep-CAM antibody;EPCAM antibody;EPCAM_HUMAN antibody;EpCAM1 antibody;Epithelial cell adhesion molecule antibody;Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody;Epithelial cell surface antigen antibody;Epithelial cellular adhesion molecule antibody;Epithelial glycoprotein 1 antibody;Epithelial glycoprotein 314 antibody;Epithelial glycoprotein antibody;ESA antibody;GA733 1 antibody;GA733 2 antibody;GA733-2 antibody;gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody;gp4 antibody;hEGP 2 antibody;hEGP314 antibody;HNPCC8 antibody;Human epithelial glycoprotein 2 antibody;KS 1/4 antigen antibody;KS1/4 antibody;KSA antibody;Ly74 antibody;Lymphocyte antigen 74 antibody;M1S 1 antibody;M1S2 antibody;M4S1 antibody;Major gastrointestinal tumor associated protein GA733 2 antibody;Major gastrointestinal tumor-associated protein GA733-2 antibody;mEGP314 antibody;Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody;Membrane component, chromosome 4, surface marker 1 antibody;Membrane component, chromosome 4, surface marker antibody;MIC18 antibody;MK 1 antibody;Protein 289A antibody;TACD1 antibody;TACSTD1 antibody;TROP1 antibody;Tumor associated calcium signal transducer 1 antibody;Tumor associated calcium signal transducer 2 precursor antibody;Tumor-associated calcium signal transducer 1 antibody

SUBCELLULAR LOCATION

Lateral cell membrane, Cell junction.

FUNCTION

EPCAM is a carcinoma-associated antigen and belongs to a family which includes at least 2 type I membrane proteins. The EPCAM protein has a role in embryonic stem cells proliferation and differentiation. EPCAM is used as a target for immunotherapy treatment of human carcinomas. EPCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and acts as a homotypic calcium-independent cell adhesion molecule. Epithelial cell adhesion molecules (EPCAM) can act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for supplying immunological barrier as a first line of defense against mucosal infection. EPCAM gene mutations result in congenital tufting enteropathy.

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