Lane 1: Jurkat
Lane 2: NIH/3T3
Mouse monoclonal primary
Eftud2 Mouse Monoclonal Antibody [1-D10-A1] (M1510-3)
Jurkat, NIH/3T3, SH-SY-5Y, SW480, mouse colon tissue, human lung cancer tissue, mouse prostate tissue, human colon cancer tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
116 kDa antibody; 116 kDa U5 small nuclear ribonucleoprotein component antibody; EFTUD2 antibody; Elongation factor Tu GTP binding domain containing 2 antibody; Elongation factor Tu GTP-binding domain-containing protein 2 antibody; hSNU114 antibody; MFDGA antibody; MFDM antibody; SNRNP116 antibody; Snrp116 antibody; Snu114 antibody; SNU114 homolog antibody; U5 116KD antibody; U5 small nuclear ribonucleoprotein component antibody; U5 snRNP specific protein, 116 kD antibody; U5 snRNP specific protein, 116 kDa antibody; U5 snRNP-specific protein antibody; U5-116 kDa antibody; U5-116KD antibody; U5S1_HUMAN antibody
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.