EBP50 Recombinant Rabbit Monoclonal Antibody [JJ0946] (ET1701-96)

UNIPROT #

O14745

PROTEIN NAME

EBP50

SYNONYMS

EBP 50 antibody;EBP50 antibody;Ezrin radixin moesin binding phosphoprotein 50 antibody;Ezrin-radixin-moesin-binding phosphoprotein 50 antibody;Na(+)/H(+) exchange regulatory cofactor NHE RF antibody;Na(+)/H(+) exchange regulatory cofactor NHE-RF1 antibody;Na+/H+ exchange regulatory co factor antibody;NHERF 1 antibody;NHERF antibody;NHERF-1 antibody;NHERF1 antibody;NHRF1_HUMAN antibody;NPHLOP2 antibody;Regulatory cofactor of Na(+)/H(+) exchanger antibody;Slc9a3r1 antibody;Sodium hydrogen exchanger regulatory factor 1 antibody;Sodium-hydrogen exchanger regulatory factor 1 antibody;Sodium/hydrogen exchanger regulatory factor 1 antibody;Solute carrier family 9 (sodium/hydrogen exchanger) member 3 regulator 1 antibody;Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 antibody;Solute carrier family 9 isoform 3 regulatory factor 1 antibody;Solute carrier family 9 isoform A3 regulatory factor 1 antibody;Solute carrier family 9 member 3 regulator 1 antibody

TISSUE SPECIFICITY

Detected in liver, kidney, pancreas, prostate, spleen, small intestine and placenta, in particular in the syncytiotrophoblast.

POST-TRANSLATIONAL MODIFICATION

Phosphorylated on serine residues.

SUBCELLULAR LOCATION

Cytoplasm, Apical cell membrane, Endomembrane system, Cell projection.

FUNCTION

Sodium-hydrogen antiporter 3 regulator 1 is a regulator of Sodium-hydrogen antiporter 3. It is encoded by the gene SLC9A3R1. It is also known as ERM Binding Protein 50 (EBP50) or Na+/H+ Exchanger Regulatory Factor (NHERF1). It is believed[5] to interact via long-range allostery, involving significant protein dynamics.