PRODUCT CODE: M1311-6

DPY30 Mouse Monoclonal Antibody [1-6] (M1311-6)

Applications

  • WB

  • ICC

REACTIVITY

  • Human

  • Mouse

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Western blot analysis on F9 cell lysates using anti-DPY30 Mouse mAb.
  • Western blot analysis on F9 cell lysates using anti-DPY30 Mouse mAb.
  • ICC staining DPY30 in F9 cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
  • ICC staining DPY30 in NCCIT cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (blue).
Western blot analysis on F9 cell lysates using anti-DPY30 Mouse mAb.

Applications

  • WB

  • ICC

REACTIVITY

  • Human

  • Mouse

SPECIFICATIONS

Product Type

Mouse monoclonal primary

Product Name

DPY30 Mouse Monoclonal Antibody [1-6] (M1311-6)

Immunogen

Peptide

Host

Mouse

Positive Control

F9

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

1-6

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

11kDa

Isotype

IgG1

APPLICATION DILUTION

  • WB

  • 1:500

TARGET

UNIPROT #

PROTEIN NAME

DPY30

SYNONYMS

Dpy-30-like protein antibody; Dpy-30L antibody; DPY30 antibody; DPY30_HUMAN antibody; HDPY-30 antibody; Protein dpy-30 homolog antibody; Saf19 antibody

SEQUENCE SIMILARITIES

Belongs to the dpy-30 family.

SUBCELLULAR LOCATION

Golgi apparatus, Nucleus

FUNCTION

As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.