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Doublecortin Recombinant Antibody [JJ0959] - Guinea pig IgG2 (Chimeric) (HA601496)

Price: Regular price $350.00

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Catalog# HA601496

to Doublecortin

Tested for

  • IHC-Fr

  • WB

Reacts with

  • Human

  • Mouse

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

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Specifications

Product Type

Recombinant Chimeric Antibody primary

Product Name

Doublecortin Recombinant Antibody [JJ0959] - Guinea pig IgG2 (Chimeric) (HA601496)

Immunogen

Synthetic peptide within human doublecortin aa 22-71 / 365.

Positive Control

SH-SY5Y cell lysate, Mouse brain (P0) tissue lysate, Mouse brain (P60) tissue lysate.

Conjugation

Unconjugated

Clone Number

JJ0959

APPLICATION DILUTION

  • IHC-Fr

  • 1::200

  • WB

  • 1:10,000

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4C. Store at +4C short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20C long term.

Storage Buffer

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 41 kDa

TARGET

UNIPROT #

O43602

PROTEIN NAME

Doublecortin

SYNONYMS

DBCN antibody;Dbct antibody;DC antibody;DCX antibody;DCX_HUMAN antibody;Doublecortex antibody;Doublin antibody;FLJ51296 antibody;Lis X antibody;Lis-X antibody;Lissencephalin X antibody;Lissencephalin-X antibody;Lissencephaly X linked antibody;Lissencephaly X linked doublecortin antibody;LISX antibody;Neuronal migration protein doublecortin antibody;OTTHUMP00000023859 antibody;OTTHUMP00000023860 antibody;OTTHUMP00000216315 antibody;OTTHUMP00000216316 antibody;SCLH antibody;XLIS antibody

SUBCELLULAR LOCATION

Cytoplasm, Cell projection, neuron projection.

FUNCTION

Neuronal migration protein doublecortin, also known as doublin or lissencephalin-X is a protein that in humans is encoded by the DCX gene. Doublecortin (DCX) is a microtubule-associated protein expressed by neuronal precursor cells and immature neurons in embryonic and adult cortical structures. Neuronal precursor cells begin to express DCX while actively dividing, and their neuronal daughter cells continue to express DCX for 2–3 weeks as the cells mature into neurons. Downregulation of DCX begins after 2 weeks, and occurs at the same time that these cells begin to express NeuN, a neuronal marker.

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