DOPEY2 Rabbit Polyclonal Antibody (0903-3)
Catalog# 0903-3
Rabbit Polyclonal to DOPEY2
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WB
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IF-Cell
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IHC-P
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FC
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Human
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Mouse
Specifications
Product Type
Rabbit polyclonal primary
Product Name
DOPEY2 Rabbit Polyclonal Antibody (0903-3)
Immunogen
Synthetic peptide within human dopey2 aa 1025-1074 / 2,298.
Host
Rabbit
Positive Control
Mouse heart, human heart, Siha, N2A, Mouse brain,
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IHC-P
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1:50-1:200
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IF-Cell
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1:50-1:500
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FC
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1:50-1:100
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 258kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
DOPEY2
SYNONYMS
Dipeptidase 2 antibody;Dipeptidase2 antibody;DPEP 2 antibody;MBD 2 antibody;MBD2 antibody
SEQUENCE SIMILARITIES
Belongs to the dopey family.
TISSUE SPECIFICITY
Ubiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients.
DEVELOPMENTAL STAGE
Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon.
SUBCELLULAR LOCATION
Early endosome membrane, Golgi apparatus membrane.
FUNCTION
Dopey-2, a 2,298 amino acid protein, belongs to the dopey family, that is overexpressed in lymphoblasts from Down syndrome patients and Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon. Multiple isoforms of Dopey-2 exist due to alternative splicing events. Dopey-2 is thought to play a role in protein trafficking between early endosomes and the late.
CITATIONS
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Dopey2 and Pcdh7 orchestrate the development of embryonic neural stem cells/ progenitors in zebrafish
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IF-Tissue
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Zebrafish
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Citation
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