Recombinant Rabbit monoclonal primary
DDAH1 Recombinant Rabbit Monoclonal Antibody [JM53-18] (ET1705-71)
Human kidney tissue lysate, human liver tissue lysate, human prostate tissue, human kidney tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
DDAH antibody; DDAH I antibody; DDAH-1 antibody; DDAH1 antibody; DDAH1_HUMAN antibody; DDAHI antibody; Dimethylargininase 1 antibody; Dimethylargininase-1 antibody; Dimethylarginine dimethylaminohydrolase 1 antibody; N(G) antibody; N(G)-dimethylarginine dimethylaminohydrolase 1 antibody; NG NG dimethylarginine dimethylaminohydrolase antibody
Belongs to the DDAH family.
Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.
DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.