DcR1 Recombinant Rabbit Monoclonal Antibody [JE58-51] (HA721475)
Catalog# HA721475
Rabbit Monoclonal to DcR1
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WB
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IF-Cell
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FC
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Human
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Mouse
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Rat
Lane 1: JAR cell lysate
Lane 2: Jurkat cell lysate
Lane 3: A549 cell lysate
Lane 4: HeLa cell lysate
Lane 5: Raji cell lysate
Lysates/proteins at 15 µg/Lane.
Predicted band size: 27 kDa
Observed band size: 27/70/80 kDa
Exposure time: 3 minutes;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA721475) at 1/1,000 dilution was used in 5% NFDM/TBST at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody (HA1001) at 1:100,000 dilution was used for 1 hour at room temperature.
Specifications
Product Type
Recombinant Rabbit monoclonal primary
Product Name
DcR1 Recombinant Rabbit Monoclonal Antibody [JE58-51] (HA721475)
Immunogen
Synthetic peptide within human dcr1 aa 200-300.
Host
Rabbit
Positive Control
JAR cell lysate, Jurkat cell lysate, A549 cell lysate, HeLa cell lysate, Raji cell lysate, Jurkat.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JE58-51
RRID
APPLICATION DILUTION
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WB
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1:1,000
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IF-Cell
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1:100
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FC
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1:500-1:1,000
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Molecular Weight
Predicted band size: 27 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
DcR1
SYNONYMS
Antagonist decoy receptor for TRAIL/Apo 2L antibody;Antagonist decoy receptor for TRAIL/Apo-2L antibody;CD263 antibody;Cytotoxic TRAIL receptor 3 antibody;DcR1 antibody;DCR1 TNFR antibody;Decoy receptor 1 antibody;Decoy TRAIL receptor without death domain antibody;LIT antibody;Lymphocyte inhibitor of TRAIL antibody;MGC149501 antibody;MGC149502 antibody;TNF related apoptosis inducing ligand receptor 3 antibody;TNF-re ated apoptosis inducing ligand receptor 3 antibody;TNF-related apoptosis-inducing ligand receptor 3 antibody;TNFRSF10C antibody;TR10C_HUMAN antibody;TRAIL R3 antibody;TRAIL receptor 3 antibody;Trail receptor without an intracellular domain antibody;TRAIL-R3 antibody;TRAILR3 antibody;TRID antibody;Tumor necrosis factor receptor superfamily member 10C antibody;Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain antibody
SUBCELLULAR LOCATION
Cell membrane.
FUNCTION
Decoy receptor 1 (DCR1), also known as TRAIL receptor 3 (TRAILR3) and tumor necrosis factor receptor superfamily member 10C (TNFRSF10C), is a human cell surface receptor of the TNF-receptor superfamily. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
CITATIONS
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Song Delei,et al
Distinct Gene Expression and Immune Features Between Different Neutrophil Extracellular Trap-Related Osteosarcoma Subtypes
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WB
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Human
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Citation
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