PRODUCT CODE: ET1612-77

Cytokeratin 9 Recombinant Rabbit Monoclonal Antibody [SD201-09] (ET1612-77)

  • Recombinant

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

  • Mouse

  • Rat

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Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 9 antibody. Counter stained with hematoxylin.

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

Cytokeratin 9 Recombinant Rabbit Monoclonal Antibody [SD201-09] (ET1612-77)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Mouse skin tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

SD201-09

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

62 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:1,000

  • IHC-P

  • 1:50-1:200

TARGET

UNIPROT #

PROTEIN NAME

Cytokeratin 9

SYNONYMS

CK 9 antibody; CK-9 antibody; Cytokeratin 9 antibody; Cytokeratin-9 antibody; Cytokeratin9 antibody; EPPK antibody; K1C9_HUMAN antibody; K9 antibody; Keratin 9 antibody; Keratin antibody; Keratin type I cytoskeletal 9 antibody; Keratin-9 antibody; Keratin9 antibody; KRT 9 antibody; Krt9 antibody; Spermatid Perinuclear Ring Manchette Protein K9 antibody; type I cytoskeletal 9 antibody

SEQUENCE SIMILARITIES

Belongs to the intermediate filament family.

TISSUE SPECIFICITY

Expressed in the terminally differentiated epidermis of palms and soles.

SUBCELLULAR LOCATION

Extracellular exosome, membrane, nucleus.

FUNCTION

Cytokeratins comprise a diverse group of intermediate filament proteins that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratin 9 is an unusually large, type I acidic cytokeratin that differentiates human plantar and palmar epidermal cells. Cytokeratin 9 localizes to the suprabasal layers as well as the upper epidermal layers such as the glandular ridges and interridges. The domains of cytokeratin 9 include a head, an α-helical coiled-coil-forming rod, and a tail; cytokeratin 9 shares significant homology with cytokeratin 10. Mutations in the cytokeratin 9 gene correlate with the development of epidermolytic palmoplantar keratoderma (EPPK), an autosomal dominant inherited skin disorder that is characterized by hyperkeratosis of the skin over the palms and soles.