Lane 1: SK-Br-3 cell lysate
Lane 2: A549 cell lysate
Lane 3: Mouse lung tissue lysate
Recombinant Rabbit monoclonal primary
Cytochrome P450 Reductase Recombinant Rabbit Monoclonal Antibody [JB54-31] (ET7107-35)
SK-Br-3, A549, mouse lung tissue lysate, rat brain tissue, human lung cancer tissue, human liver tissue, mouse testis tissue, HepG2.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Cytochrome P450 Reductase
CPR antibody; CYPOR antibody; Cytochrome p450 oxidoreductase antibody; DKFZp686G04235 antibody; FLJ26468 antibody; NADPH Cytochrome P450 Reductase antibody; NADPH dependent cytochrome P450 reductase antibody; NADPH--cytochrome P450 reductase antibody; NCPR_HUMAN antibody; P450 (cytochrome) oxidoreductase antibody; P450 Cytochrome Oxidoreductase antibody; P450R antibody; por antibody
Belongs to the NADPH--cytochrome P450 reductase family.; In the N-terminal section; belongs to the flavodoxin family.; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYPOR, also known as cytochrome P450 reductase and NADPH cytochrome P450 reductase, is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. CYPOR is localized to the endoplasmic reticulum, where it is also able to transfer electrons to heme oxygenase and cytochrome b5. CYPOR is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin. Electron transfer of CYPOR requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively.