PRODUCT CODE: ET7106-67

CSNK2B Recombinant Rabbit Monoclonal Antibody [JU37-62] (ET7106-67)

  • Recombinant

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

  • Mouse

  • Rat

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+
Western blot analysis of CSNK2B on SH-SY5Y (1) and 293 (2) lysate using anti-CSNK2B antibody at 1/500 dilution.
  • Western blot analysis of CSNK2B on SH-SY5Y (1) and 293 (2) lysate using anti-CSNK2B antibody at 1/500 dilution.
  • Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-CSNK2B antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CSNK2B antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue using anti-CSNK2B antibody. Counter stained with hematoxylin.
Western blot analysis of CSNK2B on SH-SY5Y (1) and 293 (2) lysate using anti-CSNK2B antibody at 1/500 dilution.

Applications

  • WB

  • IHC-P

  • IP

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Recombinant Rabbit monoclonal primary

Product Name

CSNK2B Recombinant Rabbit Monoclonal Antibody [JU37-62] (ET7106-67)

Immunogen

Recombinant protein

Host

Rabbit

Positive Control

Human colon cancer tissue, human breast tissue, mouse cerebellum tissue, SH-SY5Y, 293.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

JU37-62

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Protein A purified.

MOLECULAR WEIGHT

25 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500-1:2,000

  • IHC-P

  • 1:50-1:100

  • IP

  • 1:10-1:50

TARGET

UNIPROT #

PROTEIN NAME

CSNK2B

SYNONYMS

Casein kinase 2 beta polypeptide antibody; Casein kinase II beta subunit antibody; Casein kinase II subunit beta antibody; CK II beta antibody; CK2B antibody; CK2N antibody; CSK2B antibody; CSK2B_HUMAN antibody; CSNK 2B antibody; csnk2b antibody; G5A antibody; MGC138222 antibody; MGC138224 antibody; Phosvitin antibody; Protein G5a antibody

SEQUENCE SIMILARITIES

Belongs to the casein kinase 2 subunit beta family.

POST-TRANSLATIONAL MODIFICATION

Phosphorylated by alpha subunit.

SUBCELLULAR LOCATION

Nucleus. Cytoplasm.

FUNCTION

Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Ie, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.