PRODUCT CODE: ER1803-43

CNGA2 Rabbit Polyclonal Antibody (ER1803-43)

Applications

  • WB

  • IHC-P

  • FC

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of CNGA2 on SK-Br-3 cell lysate using anti-CNGA2 antibody at 1/2,000 dilution.
  • Western blot analysis of CNGA2 on SK-Br-3 cell lysate using anti-CNGA2 antibody at 1/2,000 dilution.
  • Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CNGA2 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-CNGA2 antibody. Counter stained with hematoxylin.
  • Flow cytometric analysis of PANC-1 cells with CNGA2 antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Western blot analysis of CNGA2 on SK-Br-3 cell lysate using anti-CNGA2 antibody at 1/2,000 dilution.

Applications

  • WB

  • IHC-P

  • FC

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

CNGA2 Rabbit Polyclonal Antibody (ER1803-43)

Immunogen

Synthetis peptide within mouse cnga2 aa 615-664 / 664.

Host

Rabbit

Positive Control

SK-Br-3, rat brain tissue, mouse brain tissue, PANC-1.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified.

MOLECULAR WEIGHT

76 kDa

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:1,000-1:5,000

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

TARGET

UNIPROT #

PROTEIN NAME

CNGA2

SYNONYMS

CNCA antibody; CNCA1 antibody; CNCG2 antibody; CNG 2 antibody; CNG channel alpha 2 antibody; CNG channel alpha-2 antibody; CNG-2 antibody; CNG2 antibody; CNGA 2 antibody; Cnga2 antibody; CNGA2_HUMAN antibody; Cyclic nucleotide gated cation channel 2 antibody; Cyclic nucleotide gated channel alpha 2 antibody; Cyclic nucleotide gated olfactory channel antibody; Cyclic nucleotide-gated cation channel 2 antibody; Cyclic nucleotide-gated channel alpha-2 antibody; Cyclic nucleotide-gated olfactory channel antibody; FLJ46312 antibody; OCNC1 antibody; OCNCa antibody

SEQUENCE SIMILARITIES

Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA2 subfamily.

SUBCELLULAR LOCATION

Membrane.

FUNCTION

Odorant signal transduction is probably mediated by a G-protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.

CITATIONS

  • Li, T., Yan, Z., He, S., Zh...

    Intermittent parathyroid hormone improves orthodontic retention via insulin-like growth factor-1. Oral diseases, 27(2), 290–300.

  • Zheng, Z., Zhang, X., Huang...

    Site-1 protease controls osteoclastogenesis by mediating LC3 transcription. Cell death and differentiation, 28(6), 2001–2018.