Positive control:
Lane 1: K562 cell lysate
Lane 2: Mouse lung tissue lysate
Applications
-
WB
-
FC
REACTIVITY
-
Human
-
Mouse
-
Rat
SPECIFICATIONS
Product Type
Rabbit polyclonal primary
Product Name
CLIC2 Rabbit Polyclonal Antibody (ER2001-41)
Immunogen
Recombinant protein within human clic2 aa 80-247.
Host
Rabbit
Positive Control
K562 cell lysate, mouse lung tissue lysate, K562.
Conjugation
Unconjugated
Clonality
Polyclonal
PROPERTIES
Form
Liquid
Storage Condition
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1 ug/ul
PURIFICATION
Protein affinity purified.
MOLECULAR WEIGHT
28 kDa
Isotype
IgG
APPLICATION DILUTION
-
WB
-
1:500-1:1,000
-
FC
-
1:50-1:100
TARGET
UNIPROT #
PROTEIN NAME
CLIC2
SYNONYMS
Chloride intracellular channel 2 antibody; Chloride intracellular channel protein 2 antibody; CLIC 2b antibody; CLIC2 antibody; CLIC2_HUMAN antibody; CLIC2b antibody; MRXS32 antibody; OTTHUMP00000196471 antibody; XAP 121 antibody; XAP121 antibody
SUBCELLULAR LOCATION
Cytoplasm, Membrane.
FUNCTION
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney.