Rabbit polyclonal primary
Chromogranin A Rabbit Polyclonal Antibody (ER40724)
PC12, Lovo, mouse pancreas tissue, rat pancreas tissue, human colon cancer tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified
CISY_HUMAN antibody; Citrate synthase antibody; Citrate synthase, mitochondrial antibody; citrate synthetase antibody; Cs antibody; EC 2.3.3 antibody; EC 126.96.36.199 antibody
Belongs to the chromogranin/secretogranin protein family.
CgA is O-glycosylated.
Cytoplasmic vesicle, secreted.
Chromogranin A is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A might promote the generation of secretory granules. It is used as an indicator for pancreas and prostate cancer. It might play a role in early neoplasic progression. It is also elevated in diabetes.