Lane 1: SH-SY5Y cell lysate
Lane 2: Hela cell lysate
Lane 3: human stomach tissue lysate
Lane 4: rat brain tissue lysate
Rabbit polyclonal primary
CHRNA3 Rabbit Polyclonal Antibody (ER1902-13)
Synthetic peptide within rat chrna3 aa 80-120.
SH-SY5Y cell lysate, Hela cell lysate, human stomach tissue lysate, rat brain tissue lysate, rat testis tissue, human liver carcinoma tissue, human colon carcinoma tissue, human skin tissue, human breast carcinoma tissue, human kidney tissue, human esophagus tissue, human small intestine tissue, human tonsil carcinoma tissue, SH-SY5Y.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
ACHA3_HUMAN antibody; AChR antibody; Cholinergic receptor neuronal nicotinic alpha polypeptide 3 antibody; Cholinergic receptor nicotinic alpha 3 antibody; Cholinergic receptor nicotinic alpha polypeptide 3 antibody; CHRNA 3 antibody; CHRNA3 antibody; LNCR2 antibody; MGC104879 antibody; NACHRA 3 antibody; NACHRA3 antibody; Neuronal acetylcholine receptor protein alpha 3 chain precursor antibody; Neuronal acetylcholine receptor subunit alpha 3 antibody; Neuronal acetylcholine receptor subunit alpha-3 antibody; Neuronal nicotinic acetylcholine receptor alpha 3 subunit antibody; PAOD2 antibody
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.