Lane 1: Rat heart tissue lysate
Lane 2: Mouse heart tissue lysate
Rabbit polyclonal primary
CHRNA1 Rabbit Polyclonal Antibody (ER1902-58)
Synthetic peptide within human chrna1 aa 1-50 / 482.
Rat heart tissue lysates, human fetal skeletal muscle tissue, mouse skeletal muscle tissue, mouse heart tissue, A549.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size: 54 kDa.
Acetylcholine receptor subunit alpha antibody; ACHA_HUMAN antibody; AChR antibody; ACHRA antibody; ACHRD antibody; CHNRA antibody; Cholinergic receptor nicotinic alpha 1 subunit antibody; Cholinergic receptor nicotinic alpha polypeptide 1 antibody; Cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) antibody; Chrna1 antibody; CMS1A antibody; CMS1B antibody; CMS2A antibody; FCCMS antibody; Nicotinic cholinergic receptor alpha 1 antibody; SCCMS antibody; Schizophrenia neurophysiologic defect candidate antibody
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Postsynaptic cell membrane, cell membrane.
Neuronal acetylcholine receptor subunit alpha-1, also known as nAChRα1, is a protein that in humans is encoded by the CHRNA1 gene. The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR). The muscle acetylcholine receptor consists of 5 subunits of 4 different types: 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 This gene encodes an alpha subunit that plays a role in acetylcholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.