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CDX2 Recombinant Rabbit Monoclonal Antibody [SY09-02] (ET1605-4)

Price: Regular price $385.00

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Catalog# ET1605-4

Rabbit Monoclonal to CDX2

Tested for

  • WB

  • IF-Cell

  • IF-Tissue

  • IHC-P

  • FC

React with

  • Human

  • Rat

Recombinant production enables lot-to-lot consistency and is animal-cruelty-free

Specifications

Product Type

Recombinant Rabbit monoclonal primary

Product Name

CDX2 Recombinant Rabbit Monoclonal Antibody [SY09-02] (ET1605-4)

Immunogen

Synthetic peptide within human cdx2 aa 20-60.

Host

Rabbit

Positive Control

AGS cell lysates, LOVO, AGS, human colon carcinoma tissue, rat large intestine tissue, Hela,human human colon tissue,human colon carcinoma tissue,human appendix tissue.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

SY09-02

APPLICATION DILUTION

  • WB

  • 1:1,000-1:2,000

  • IF-Cell

  • 1:50-1:200

  • IF-Tissue

  • 1:50-1:200

  • IHC-P

  • 1:500

  • FC

  • 1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1ug/ul

Purification

Protein A affinity purified.

Molecular Weight

34 kDa

Isotype

IgG

TARGET

UNIPROT #

Q99626

PROTEIN NAME

CDX2

SYNONYMS

Caudal type homeo box 2 antibody;Caudal type homeo box transcription factor 2 antibody;Caudal type homeobox 2 antibody;Caudal type homeobox protein 2 antibody;Caudal type homeobox transcription factor 2 antibody;Caudal-type homeobox protein 2 antibody;CDX 2 antibody;CDX 3 antibody;CDX-3 antibody;Cdx2 antibody;CDX2_HUMAN antibody;CDX3 antibody;Homeobox protein CDX 2 antibody;Homeobox protein CDX-2 antibody

SEQUENCE SIMILARITIES

Belongs to the Caudal homeobox family.

POST-TRANSLATIONAL MODIFICATION

Phosphorylation of Ser-60 mediates the transactivation capacity.

SUBCELLULAR LOCATION

Nucleus.

FUNCTION

In common with the two other Cdx genes, CDX2 regulates several essential processes in the development and function of the lower gastrointestinal tract (from the duodenum to the anus) in vertebrates. In vertebrate embryonic development, CDX2 becomes active in endodermal cells that are posterior to the developing stomach.These cells eventually form the intestinal epithelium. The activity of CDX2 at this stage is essential for the correct formation of the intestine and the anus.CDX2 is also required for the development of the placenta.

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