Rabbit polyclonal primary
CD8 Rabbit Polyclonal Antibody (0108-7)
Synthetic peptide within mouse cd8 aa30-70.
Mouse thymus tisue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Immunogen affinity purified
CD8 antibody; CD8 antigen, alpha polypeptide (p32) antibody; CD8a antibody; CD8a antigen antibody; CD8a molecule antibody; CD8A_HUMAN antibody; Leu2 antibody; Leu2 T lymphocyte antigen antibody; MAL antibody; OKT8 T cell antigen antibody; p32 antibody; T cell antigen Leu2 antibody; T cell co receptor antibody; T-cell surface glycoprotein CD8 alpha chain antibody; T-lymphocyte differentiation antigen T8/Leu-2 antibody; T8 T cell antigen antibody
Palmitoylated, but association with CD8B seems to be more important for the enrichment of CdD8A in lipid rafts.; Phosphorylated in cytotoxic T-lymphocytes (CTLs) following activation.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. CD8 is thought to play a role in the process of T-cell mediated killing.