Line2: Human placenta
Recombinant Rabbit monoclonal primary
CD62P Recombinant Rabbit Monoclonal Antibody [JM10-95] (ET1703-49)
HUVEC, human placenta, human tonsil tissue, human spleen tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Antigen CD62 antibody; CD62 antibody; CD62 antigen-like family member P antibody; CD62P antibody; GMP 140 antibody; GMP-140 antibody; GMP140 antibody; GMRP antibody; Granule membrane protein 140 antibody; Granulocyte membrane protein antibody; GRMP antibody; LECAM 3 antibody; LECAM3 antibody; Leukocyte endothelial cell adhesion molecule 3 antibody; Leukocyte-endothelial cell adhesion molecule 3 antibody; LYAM3_HUMAN antibody; P Selectin antibody; P-selectin antibody; PADGEM antibody; Platelet activation dependent granule-external membrane protein antibody; Platelet alpha granule membrane protein antibody; PSEL antibody; Selectin P (granule membrane protein 140kDa, antigen CD62) antibody; SELP antibody
Belongs to the selectin/LECAM family.
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes.