Rabbit polyclonal primary
CD55 Rabbit Polyclonal Antibody (ER1802-46)
Recombinant protein within human cd55 aa 130-381.
Hela and PC-3M cell lysates, human plasma, human colon cancer tissue, human placenta tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein affinity purified.
42/49/60 kDa (Predicted band size)
CD 55 antibody; CD55 antibody; CD55 antigen antibody; CD55 Cromer blood group system antibody; CD55 molecule (Cromer blood group) antibody; CD55 molecule antibody; CD55 molecule, decay accelerating factor for complement (Cromer blood group) antibody; Cd55a antibody; Complement decay accelerating factor antibody; Complement decay-accelerating factor antibody; Complement decay-accelerating factor, GPI-anchored antibody; CR antibody; CROM antibody; Cromer Blood Group antigen antibody; Cromer blood group system antibody; DAF antibody; Daf-GPI antibody; DAF_HUMAN antibody; Daf1 antibody; Dcay accelerating factor for complement (CD55, Cromer blood group system) antibody; Decay accelarating factor 1, isoform CRA_a antibody; Decay accelerating factor (GPI-form) antibody; Decay Accelerating Factor for Complement antibody; Decay accelerating factor GPI-form antibody; Decay accelerating factor soluble-form antibody; GPI-DAF antibody; TC antibody
Belongs to the receptors of complement activation (RCA) family.
Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
The Ser/Thr-rich domain is heavily O-glycosylated.
Cell membrane. Secreted.
CD55, also called decay accelerating factor (DAF), is a GPI-anchored single chain glycoprotein. CD55 may play a role in protecting cells from complement-mediated lysis by preventing the amplification steps of the complement cascade. CD55 functions to prevent the assembly of C3 convertase or to accelerate the disassembly of preformed convertase, which blocks formation of the membrane attack complex. CD55 is expressed on cells in contact with serum, including hematopoietic and many non-hematopoietic cells.