Mouse monoclonal primary
CD55 Mouse Monoclonal Antibody [12F1] (EM1902-42)
Recombinant protein within human cd55 aa 150- 381.
Store at +4Á¾ after thawing. Aliquot store at -20Á¾. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein G affinity purified.
Predicted band size: 41 kDa.
CD 55 antibody; CD55 antibody; CD55 antigen antibody; CD55 Cromer blood group system antibody; CD55 molecule (Cromer blood group) antibody; CD55 molecule antibody; CD55 molecule, decay accelerating factor for complement (Cromer blood group) antibody; Cd55a antibody; Complement decay accelerating factor antibody; Complement decay-accelerating factor antibody; Complement decay-accelerating factor, GPI-anchored antibody; CR antibody; CROM antibody; Cromer Blood Group antigen antibody; Cromer blood group system antibody; DAF antibody; Daf-GPI antibody; DAF_HUMAN antibody; Daf1 antibody; Dcay accelerating factor for complement (CD55, Cromer blood group system) antibody; Decay accelarating factor 1, isoform CRA_a antibody; Decay accelerating factor (GPI-form) antibody; Decay Accelerating Factor for Complement antibody; Decay accelerating factor GPI-form antibody; Decay accelerating factor soluble-form antibody; GPI-DAF antibody; TC antibody
Cell membrane, Membrane, Secreted.
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade . Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage .