CD36 Rabbit Polyclonal Antibody (ER1802-7)
Catalog# ER1802-7
Rabbit Polyclonal to CD36
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IF-Cell
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IHC-P
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FC
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Human
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Mouse
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Rat
Specifications
Product Type
Rabbit polyclonal primary
Product Name
CD36 Rabbit Polyclonal Antibody (ER1802-7)
Immunogen
Synthetic peptide within human cd36 aa 55-117.
Host
Rabbit
Positive Control
HepG2, HUVEC, SH-SY5Y, rat heart tissue, mouse small intestine tissue, mouse heart tissue, THP-1.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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IF-Cell
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1:50-1:100
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IHC-P
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1:50-1:200
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FC
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1:50-1:100
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 53 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
CD36
SYNONYMS
Adipocyte membrane protein antibody;BDPLT10 antibody;CD36 antibody;CD36 antigen (collagen type I receptor, thrombospondin receptor) antibody;CD36 antigen antibody;CD36 molecule (thrombospondin receptor) antibody;CD36 molecule antibody;CD36_HUMAN antibody;CHDS7 antibody;Cluster determinant 36 antibody;Collagen receptor, platelet antibody;FAT antibody;Fatty acid translocase antibody;Fatty acid transport protein antibody;Glycoprotein IIIb antibody;GP IIIb antibody;GP3B antibody;GP4 antibody;GPIIIB antibody;GPIV antibody;Leukocyte differentiation antigen CD36 antibody;MGC108510 antibody;MGC91634 antibody;PAS 4 protein antibody;PAS IV antibody;PAS-4 antibody;PASIV antibody;Platelet collagen receptor antibody;Platelet glycoprotein 4 antibody;Platelet glycoprotein IV antibody;scarb3 antibody;Scavenger receptor class B member 3 antibody;Thrombospondin receptor antibody
SEQUENCE SIMILARITIES
Belongs to the CD36 family.
POST-TRANSLATIONAL MODIFICATION
N-glycosylated and O-glycosylated with a ratio of 2:1.; Ubiquitinated at Lys-469 and Lys-472. Ubiquitination is induced by fatty acids such as oleic acid and leads to degradation by the proteasome. Ubiquitination and degradation are inhibited by insulin which blocks the effect of fatty acids.
SUBCELLULAR LOCATION
Cell membrane, Golgi apparatus, Apical cell membrane.
FUNCTION
CD36 (collagen type I receptor, thrombospondin receptor, FAT, GP4, GP3B, GPIV, PASIV, SCARB3) is a membrane glycoprotein on platelets, monocytes and umbilical vein endothelial cells. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. CD36 plays a key role in both phagocytosis and lipid recycling, for constant production of mature spermatozoa. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. Thrombospondins are widely distributed proteins that influence a variety of adhesive processes and CD36 may have important functions as a cell adhesion molecule.
CITATIONS
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Bioinformatics analysis reveals lipid metabolism may play an important role in the SiO2-stimulated rat model
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WB
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Rat
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Citation
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