Mouse monoclonal primary
CD34 Mouse Monoclonal Antibody [15H1] (EM1901-01)
Recombinant protein within human cd34 aa 32-322 / 385.
Rat brain tissue, rat kidney tissue, human liver carcinoma tissue, mouse kidney tissue, human placenta tissue, human endometrium tissue, THP-1.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Protein G purified.
41 kDa (Predicted band size)
CD34 antibody; CD34 antigen antibody; CD34 molecule antibody; CD34_HUMAN antibody; Cluster designation 34 antibody; Hematopoietic progenitor cell antigen CD34 antibody; HPCA1 antibody; Mucosialin antibody; OTTHUMP00000034733 antibody; OTTHUMP00000034734 antibody
Belongs to the CD34 family.
Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
On early hematopoietic progenitor cells.
Highly glycosylated.; Phosphorylated on serine residues by PKC.
Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,function:Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.,