CD24 Rabbit Polyclonal Antibody (0804-4)
Catalog# 0804-4
Rabbit Polyclonal to CD24
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WB
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IF-Cell
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FC
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Human
Specifications
Product Type
Rabbit polyclonal primary
Product Name
CD24 Rabbit Polyclonal Antibody (0804-4)
Immunogen
Synthetic peptide within human cd24 aa 31-80 / 80.
Host
Rabbit
Positive Control
Human spleen tissue lysates, Hela, SW480, MCF-7.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
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WB
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1:500-1:1,000
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IF-Cell
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1:50-1:200
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FC
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1:50-1:100
PROPERTIES
Form
Liquid
Storage Condition
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 8 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
CD24
SYNONYMS
CD 24 antibody;CD24 antibody;CD24 antigen (small cell lung carcinoma cluster 4 antigen) antibody;CD24 antigen antibody;CD24 molecule antibody;CD24_HUMAN antibody;CD24A antibody;FLJ22950 antibody;FLJ43543 antibody;GPI linked surface mucin antibody;Heat stable antigen antibody;HSA antibody;MGC75043 antibody;Nectadrin antibody;Signal transducer CD24 antibody;Small cell lung carcinoma cluster 4 antigen antibody
SEQUENCE SIMILARITIES
Belongs to the CD24 family.
TISSUE SPECIFICITY
B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells.
POST-TRANSLATIONAL MODIFICATION
Extensively O-glycosylated.
SUBCELLULAR LOCATION
Cell membrane.
FUNCTION
The human CD24 antigen is a small heavily glycosylated, glycosylphosphatidylinositol (GPI) linked cell surface protein. It consists of a small protein core comprising 27 amino acids, which is extensively glycosylated and is bound to the membrane via a phosphatidylinositol anchor. The human CD24 antigen is physiologically expressed in developing or regenerating tissue, as well as in granulocytes, keratinocytes and renal tubular epithelium. It modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor
CITATIONS
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Gang Feng
Tex10 promotes stemness and EMT phenotypes in esophageal squamous cell carcinoma via the Wnt/β-catenin pathway
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WB
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Human
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Citation
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