CCL3 / MIP-1 alpha Rabbit Polyclonal Antibody (R1510-9)
Catalog# R1510-9
Rabbit Polyclonal to CCL3
-
IF-Cell
-
IHC-P
-
FC
-
ELISA
-
Human
-
Mouse
-
Rat
Specifications
Product Type
Rabbit polyclonal primary
Product Name
CCL3 / MIP-1 alpha Rabbit Polyclonal Antibody (R1510-9)
Immunogen
Synthetic peptide within mouse ccl3 aa 43-92 / 92.
Host
Rabbit
Positive Control
PANC-1, A549, mouse pancreas tissue, mouse lung tissue, mouse spleen tissue.
Conjugation
Unconjugated
Clonality
Polyclonal
RRID
APPLICATION DILUTION
-
IF-Cell
-
1:50-1:200
-
IHC-P
-
1:50-1:200
-
FC
-
1:50-1:100
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Immunogen affinity purified.
Molecular Weight
Predicted band size: 10 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
CCL3
SYNONYMS
C C motif chemokine 3 antibody;CCL 3 antibody;CCL3 antibody;CCL3_HUMAN antibody;Chemokine C C motif ligand 3 antibody;G0/G1 switch regulatory protein 19 1 antibody;G0/G1 switch regulatory protein 19-1 antibody;G0S19 1 antibody;G0S19 1 protein antibody;Heparin binding chemotaxis protein antibody;L2G25B antibody;LD78 alpha antibody;LD78-alpha(4-69) antibody;LD78alpha antibody;Macrophage inflammatory protein 1 alpha antibody;Macrophage inflammatory protein 1-alpha antibody;MIP 1 alpha antibody;MIP 1A antibody;MIP-1-alpha antibody;MIP-1-alpha(4-69) antibody;MIP1A antibody;PAT 464.1 antibody;SCYA 3 antibody;SCYA3 antibody;SIS alpha antibody;SIS beta antibody;SIS-beta antibody;Small inducible cytokine A3 antibody;small inducible cytokine A3 (homologous to mouse Mip-1a) antibody;Small-inducible cytokine A3 antibody;Tonsillar lymphocyte LD78 alpha protein antibody
SEQUENCE SIMILARITIES
Belongs to the intercrine beta (chemokine CC) family.
TISSUE SPECIFICITY
Expressed in lung, spleen, and pancreas.
SUBCELLULAR LOCATION
Secreted
FUNCTION
Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1α, MIP-1β, MIP-2, MIP-3α, MIP-3β, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. Research has shown that MIP-1β is more selective than MIP-1α, primarily attracting CD4+ T lymphocytes, with a preference for T cells of the naive phenotype. MIP-1α is a more potent lymphocyte chemoattractant than MIP-1β and exhibits a broader range of chemoattractant specificities. It has been suggested that CD8+ T lymphocytes are involved in the control of HIV infection in vivo by the release of HIV-suppressive factors (HIV-SF). MIP-1α has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1β and RANTES
CITATIONS
-
Li Zheng,et al
Tracing Immunological Interaction in Trimethylamine N-Oxide Hydrogel-Derived Zwitterionic Microenvironment During Promoted Diabetic Wound Regeneration
-
IF
-
Mouse
-
Citation
-
