Lane 1: HepG2
Lane 2: Hela
Recombinant Rabbit monoclonal primary
Cathepsin B Recombinant Rabbit Monoclonal Antibody [JA11-02] (ET1704-03)
HepG2, A549, Hela, human liver tissue, human liver cancer tissue, human pancreas tissue, mouse pancreas tissue, mouse brain tissue.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Amyloid precursor protein secretase antibody; APP secretase antibody; APPS antibody; CATB_HUMAN antibody; Cathepsin B heavy chain antibody; Cathepsin B1 antibody; CathepsinB antibody; CPSB antibody; CTSB antibody; cysteine protease antibody; OTTHUMP00000116009 antibody; OTTHUMP00000229510 antibody; OTTHUMP00000229511 antibody; OTTHUMP00000229512 antibody; OTTHUMP00000229514 antibody; OTTHUMP00000229515 antibody; OTTHUMP00000229516 antibody; Preprocathepsin B antibody
Belongs to the peptidase C1 family.
Expressed in the stratum spinosum of the epidermis. Weak expression is detected in the stratum granulosum.
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.