Carbonic anhydrase 2 Recombinant Rabbit Monoclonal Antibody [JU12-37] (ET1706-47)
Catalog# ET1706-47
Rabbit Monoclonal to Carbonic anhydrase 2
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WB
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IHC-P
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IHC-Fr
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Human
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Mouse
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Rat
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Cynomolgus monkey
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Pig
Species: Mouse
Site: Striatum
Sample: Frozen section
Antibody concentration: 1:500
Antigen retrieval: Recommend. The section was pre-treated using 1% SDS buffer (in PBS, pH 7.4) for 5 minutes at room temperature (recommend).
Specifications
Product Type
Recombinant Rabbit monoclonal primary
Product Name
Carbonic anhydrase 2 Recombinant Rabbit Monoclonal Antibody [JU12-37] (ET1706-47)
Immunogen
Synthetic peptide within human carbonic anhydrase ii aa 211-260 / 260.
Host
Rabbit
Positive Control
Mouse kidney tissue lysate, Mouse P0 brain tissue lysate, Mouse adult brain tissue lysate, Rat kidney tissue lysate, Rat adult brain tissue lysate, Mouse brain tissue lysate, 293T cell lysate, Rat colon tissue lysate, Rat liver tissue lysate, mouse brain tissue, mouse striatum tissue, rat cerebral cortex tissue, rat striatum tissue.
Conjugation
Unconjugated
Clonality
Monoclonal
Clone Number
JU12-37
RRID
APPLICATION DILUTION
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WB
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1:2,000-1:5,000
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IHC-P
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1:200-1:1,000
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IHC-Fr
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1:500
PROPERTIES
Form
Liquid
Storage Condition
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
Storage Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Concentration
1ug/ul
Purification
Protein A affinity purified.
Molecular Weight
Predicted band size: 29 kDa
Isotype
IgG
TARGET
UNIPROT #
PROTEIN NAME
Carbonic anhydrase 2
SYNONYMS
CA 2 antibody;CA II antibody;CA-II antibody;Ca2 antibody;CAC antibody;CAH2_HUMAN antibody;CAII antibody;Car 2 antibody;Car2 antibody;Carbonate dehydratase II antibody;Carbonic anhydrase 2 antibody;Carbonic anhydrase B antibody;Carbonic anhydrase C antibody;Carbonic anhydrase C, formerly antibody;Carbonic anhydrase II antibody;Carbonic dehydratase antibody;epididymis luminal protein 76 antibody;Epididymis secretory protein Li 282 antibody;HEL-76 antibody;HEL-S-282 antibody
SEQUENCE SIMILARITIES
Belongs to the alpha-carbonic anhydrase family.
SUBCELLULAR LOCATION
Cytoplasm.
FUNCTION
Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes including respiration, calcification, acid-base balance and bone resorption, as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA2 gene, which maps to chromosome 8q21, encodes CA II, a cytoplasmic protein that has the highest turnover rate and widest tissue distribution of any known human CA isozyme. The human CA4 gene, which maps to chromosome 17q23, encodes CA IV, a membrane-anchored isozyme that is expressed on the luminal surfaces of pulmonary capillaries and proximal renal tubules. The human CA9, CA12 and CA14 genes, which map to chromosomes 9p13, 15q22 and 1q21, respectively, encode transmembrane proteins that have unique patterns of tissue-specific expression.
CITATIONS
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Wang, Y., Li, X., Deng, F., & Yin, R.
Hydroxy-Safflower Yellow A Alleviates Osteoporosis in Ovariectomized Rat Model by Inhibiting Carbonic Anhydrase 2 Activity
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WB
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Rat
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Citation
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