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CAPZA1 Mouse Monoclonal Antibody [A2E7] (EM1901-82)

Price: Regular price $325.00

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Catalog# EM1901-82

Mouse Monoclonal to CAPZA1

Tested for

  • WB

  • ICC

  • IHC-P

  • FC

React with

  • Human

Specifications

Product Type

Mouse monoclonal primary

Product Name

CAPZA1 Mouse Monoclonal Antibody [A2E7] (EM1901-82)

Immunogen

Recombinant protein within human capza1 aa 60-248 / 286.

Host

Mouse

Positive Control

K562 cell lysates, A431, SiHa, human prostate carcinoma tissue, human kidney tissue, HL-60.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

A2E7

APPLICATION DILUTION

  • WB:1:500-1:1,000

  • ICC:1:50-1:100

  • IHC-P:1:50-1:200

  • FC:1:50-1:100

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein G affinity purified.

Molecular Weight

33 kDa

Isotype

IgG1

TARGET

UNIPROT #

P52907

PROTEIN NAME

CAPZA1

SYNONYMS

Cap Z antibody;Cappa 1 antibody;Cappa1 antibody;Capping protein (actin filament) muscle Z line alpha 1 antibody;Capping protein alpha 1 antibody;Capping protein muscle Z line alpha 1 antibody;CapZ alpha 1 antibody;CapZ alpha-1 antibody;CAPZ antibody;CAPZA 1 antibody;Capza1 antibody;CAZ 1 antibody;CAZ1 antibody;CAZA1_HUMAN antibody;F actin capping protein alpha 1 subunit antibody;F-actin-capping protein subunit alpha-1 antibody

SEQUENCE SIMILARITIES

Belongs to the F-actin-capping protein alpha subunit family.

SUBCELLULAR LOCATION

Cytoskeleton.

FUNCTION

CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein. The protein regulates growth of the actin filament by capping the barbed end of growing actin filaments. F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions.

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