Recombinant Rabbit monoclonal primary
Calsequestrin 1 Recombinant Rabbit Monoclonal Antibody [JB57-37] (ET7107-39)
Recombinant protein within human calsequestrin 1 aa 80-220 / 396.
Rat skeletal muscle tissue, mouse skeletal muscle tissue, human fetal skeletal muscle tissue, C2C12.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
Calmitin antibody; Calmitine antibody; Calsequestrin 1 (fast twitch, skeletal muscle) antibody; Calsequestrin antibody; Calsequestrin, cell antibody; Calsequestrin, skeletal muscle isoform antibody; Calsequestrin-1 antibody; CASQ antibody; Casq1 antibody; CASQ1_HUMAN antibody; PDIB1 antibody; skeletal muscle isoform antibody
Belongs to the calsequestrin family.
Expressed in myoblasts (at protein level).
Endoplasmic reticulum. Mitochondrion.
Calsequestrin (CS, also known as CSQ) is the major calcium-binding protein of cardiac and skeletal muscle whose function is to sequester calcium in the lumen of the sarcoplasmic reticulum (SR). In mammals, there are two forms of this protein, calsequestrin 1 and calsequestrin 2, which encode fast-twitch skeletal muscle and cardiac calsequestrin, respectively. Calsequestrin 1, also known as Calmitin, is located in the terminal cisternae luminal spaces of the SR of fast skeletal muscle cells. Calsequestrin 2 is present in terminal cisternae luminal spaces of the SR of both cardiac and slow skeletal muscle cells. In addition, calsequestrin regulates the ryanodine receptor signaling (RyR) through Triadin and Junctin.