CacyBP Rabbit Polyclonal Antibody (HA500484)

UNIPROT #

Q9HB71

PROTEIN NAME

CacyBP

SYNONYMS

CacyBP antibody;Calcyclin binding protein antibody;Calcyclin-binding protein antibody;CYBP_HUMAN antibody;GIG 5 antibody;GIG5 antibody;Growth inhibiting gene 5 antibody;Growth inhibiting gene 5 protein antibody;hCacyBP antibody;MGC87971 antibody;PNAS 107 antibody;PNAS107 antibody;RP1 102G20.6 antibody;S100A6 binding protein antibody;S100A6-binding protein antibody;S100A6BP antibody;Siah-interacting protein antibody;SIP antibody

SUBCELLULAR LOCATION

Nucleus, Cytoplasm.

FUNCTION

Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene. The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. CACYBP has been shown to interact with SKP1A and SIAH1.T he CacyBP/SIP complex instead, is known to be a part of stress respons, since it interacts with chaperone HSP90.