Lane 1: Anti-CACNG3 Antibody (1:500).
Lane 2: Anti-CACNG3 Antibody, pre-incubated with the immunizaiton peptide.
Rabbit polyclonal primary
CACNG3 Rabbit Polyclonal Antibody (ER1803-38)
Synthetic peptide within rat cacng3 aa 192-241 / 315.
SH-SY-5Y, rat brain tissue.
Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Peptide affinity purified.
Predicted band size 36 kDa
CACNG 3 antibody; Cacng2 antibody; CACNG3 antibody; Calcium channel voltage dependent gamma subunit 3 antibody; CCG3_HUMAN antibody; Neuronal voltage gated calcium channel gamma 3 subunit antibody; Neuronal voltage-gated calcium channel gamma-3 subunit antibody; TARP gamma-3 antibody; Transmembrane AMPAR regulatory protein gamma-3 antibody; Voltage dependent calcium channel gamma 3 subunit antibody; Voltage gated calcium channel gamma subunit antibody; Voltage-dependent calcium channel gamma-3 subunit antibody
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
Membrane. Displays a somatodendritic localization and is excluded from axons in neurons.
Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.