PRODUCT CODE: ER1803-24

CACNB3 Rabbit Polyclonal Antibody (ER1803-24)

Applications

  • WB

  • IHC-P

  • FC

REACTIVITY

  • Human

  • Mouse

  • Rat

Western blot analysis of CACNB3 on different lysates using anti-CACNB3 antibody at 1/500 dilution.<br />
 Positive control:<br />
 Lane 1: Rat brain tissue<br />
   Lane 2: SKOV-3
  • Western blot analysis of CACNB3 on different lysates using anti-CACNB3 antibody at 1/500 dilution.<br />
 Positive control:<br />
 Lane 1: Rat brain tissue<br />
   Lane 2: SKOV-3
  • Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CACNB3 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-CACNB3 antibody. Counter stained with hematoxylin.
  • Immunohistochemical analysis of paraffin-embedded mouse ovary tissue using anti-CACNB3 antibody. Counter stained with hematoxylin.
  • Flow cytometric analysis of SKOV-3 cells with CACNB3 antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
Western blot analysis of CACNB3 on different lysates using anti-CACNB3 antibody at 1/500 dilution.
Positive control:
Lane 1: Rat brain tissue
Lane 2: SKOV-3

Applications

  • WB

  • IHC-P

  • FC

REACTIVITY

  • Human

  • Mouse

  • Rat

SPECIFICATIONS

Product Type

Rabbit polyclonal primary

Product Name

CACNB3 Rabbit Polyclonal Antibody (ER1803-24)

Immunogen

Synthetic peptide within human cacnb3 aa 435-484 / 484.

Host

Rabbit

Positive Control

Rat brain tissue lysate, SKOV-3, human uterus tissue, mouse ovary tissue.

Conjugation

Unconjugated

Clonality

Polyclonal

PROPERTIES

Form

Liquid

Storage Condition

Store at +4C after thawing. Aliquot store at -20C. Avoid repeated freeze / thaw cycles.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

1 ug/ul

PURIFICATION

Peptide affinity purified.

MOLECULAR WEIGHT

55 kDa (Predicted band size)

Isotype

IgG

APPLICATION DILUTION

  • WB

  • 1:500

  • IHC-P

  • 1:50-1:200

  • FC

  • 1:50-1:100

TARGET

UNIPROT #

PROTEIN NAME

CACNB3

SYNONYMS

CAB3 antibody; CACB3_HUMAN antibody; Cacnb3 antibody; CACNLB3 antibody; Calcium channel voltage dependent beta 3 subunit antibody; Calcium channel voltage-dependent subunit beta 3 antibody; FLJ58949 antibody; Voltage-dependent L-type calcium channel subunit beta-3 antibody

SEQUENCE SIMILARITIES

Belongs to the calcium channel beta subunit family.

TISSUE SPECIFICITY

Expressed mostly in brain, colon and ovary.

SUBCELLULAR LOCATION

Cytoplasm.

FUNCTION

Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.