Skip to content

Contact

(857) 353-6600

orders@huabio.com

C10orf58 Mouse Monoclonal Antibody [7-B7] (M1012-4)

Price: Regular price $350.00

Unit price per 

Volume

Bulk Order Quote   |   Customization Request

Catalog# M1012-4

Mouse Monoclonal to C10orf58

Tested for

  • WB

  • IF-Cell

Reacts with

  • Human

Safety datasheet

Select your chosen country/region

COA DOWNLOAD

Specifications

Product Type

Mouse monoclonal primary

Product Name

C10orf58 Mouse Monoclonal Antibody [7-B7] (M1012-4)

Immunogen

Recombinant protein within human c10orf58 aa 1-229 / 229.

Host

Mouse

Positive Control

Recombinant protein, human skin tissue lysate, HepG2, HUVEC, PC-3M.

Conjugation

Unconjugated

Clonality

Monoclonal

Clone Number

7-B7

RRID

AB_3073036

APPLICATION DILUTION

  • WB

  • 1:500

  • IF-Cell

  • 1:50-1:200

PROPERTIES

Form

Liquid

Storage Condition

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.

Storage Buffer

1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration

2ug/ul

Purification

Protein A affinity purified.

Molecular Weight

Predicted band size: 26 kDa

Isotype

IgG2a

TARGET

UNIPROT #

Q9BRX8

PROTEIN NAME

C10orf58

SYNONYMS

C10orf58 antibody;CJ058_HUMAN antibody;UPF0765 protein C10orf58 antibody

SEQUENCE SIMILARITIES

Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.

TISSUE SPECIFICITY

Expressed in CSF1 and TNFSF11-stimulated CD14(+) peripheral blood mononuclear cells (PBMCs).

SUBCELLULAR LOCATION

Cytoplasm, Secreted.

FUNCTION

FAM213A, also known as PAMM (peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) or C10orf58, is a 229 amino acid cytoplasmic protein that belongs to the peroxiredoxin-like FAM213 family and FAM213A subfamily. FAM213A involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.

Close (esc)

Popup

Use this popup to embed a mailing list sign up form. Alternatively use it as a simple call to action with a link to a product or a page.

Age verification

By clicking enter you are verifying that you are old enough to consume alcohol.

Enter

Search

Main menu

Your cart is currently empty.
Shop now