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beta Amyloid 1-42 Protein (HA210499)

Price: Regular price $100.00

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Catalog# HA210499

Reacts with

  • Human

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Product Details

Product Type

Protein

Product Name

beta Amyloid 1-42 Protein (HA210499)

Predicted molecular mass

4.5 kD

Protein construction description

DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA (P05067:672-713aa)

Accession

P05067

Source

Synthetic peptide.

Purity

85.18%

Formulation

Soluble in PBS.

Species

Human

Background

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. This antibody does not cross-react with Mouse beta Amyloid 1-42.

Usage Guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.

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