Lane 1: Hela cell lysate
Lane 2: human skeletal muscle tissue lysate
Lane 3: AGS cell lysate
Recombinant Rabbit monoclonal primary
Bak Recombinant Rabbit Monoclonal Antibody [SU32-07] (ET1608-21)
Synthetic peptide within human bak aa 1-50 / 211.
Hela cell lysate, human skeletal muscle tissue lysate, AGS cell lysate, CRC, human lung tissue, mouse lung tissue, human stomach carcinoma tissue, NIH/3T3.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A affinity purified.
Apoptosis regulator BAK antibody; BAK antibody; BAK like antibody; Bak NT antibody; BAK_HUMAN antibody; Bak1 antibody; Bcl 2 homologous antagonist/killer antibody; Bcl 2 like 7 protein antibody; Bcl-2 homologous antagonist/killer antibody; Bcl-2-like protein 7 antibody; BCL2 antagonist/killer 1 antibody; Bcl2 like 7 Protein antibody; Bcl2-L-7 antibody; BCL2L7 antibody; CDN1 antibody; Cell death inhibitor 1 antibody; MGC117255 antibody; MGC3887 antibody; NBak antibody; Pro apoptotic protein BAK antibody
Belongs to the Bcl-2 family.
Expressed in a wide variety of tissues, with highest levels in the heart and skeletal muscle.
The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiologic conditions. Bcl-2 and several related proteins function to inhibit apoptosis, while other members of the Bcl-2 family, such as Bax, accelerate death under various conditions. One member of the Bcl-2 family, designated Bak, functions primarily to enhance apoptotic cell death following appropriate activating signals and counteracts the protection from apoptosis provided by Bcl-2. Expression of Bak is widespread in a broad range of cells, including various long-lived, terminally differentiated cell types, suggesting that its cell-death-inducing activity is broadly distributed and that the regulation of inhibitors of apoptosis may represent an important determinant of tissue-specific modulation of apoptosis.