Lane 1: Mouse kidney tissue
Lane 2: CRC
Rabbit polyclonal primary
AXL Rabbit Polyclonal Antibody (R1406-3)
Recombinant protein within human axl 1-200 aa.
Mouse kidney tissue lysate, CRC cell lysate, human AXL recombinant protein lysate, Hela, LOVO, MCF-7.
Store at +4C after thawing. Aliquot store at -20C or -80C. Avoid repeated freeze / thaw cycles.
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Protein A purified.
98 kDa(Predicted band)
Adhesion related kinase antibody; AI323647 antibody; Ark antibody; Axl antibody; AXL oncogene antibody; AXL receptor tyrosine kinase antibody; AXL transforming gene antibody; AXL transforming sequence/gene antibody; EC 188.8.131.52 antibody; JTK11 antibody; Oncogene AXL antibody; Tyro7 antibody; Tyrosine protein kinase receptor UFO antibody; Tyrosine-protein kinase receptor UFO antibody; UFO antibody; UFO_HUMAN antibody
Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily.
Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
Monoubiquitinated upon GAS6-binding. A very small proportion of the receptor could be subjected to polyubiquitination in a very transient fashion.; Phosphorylated at tyrosine residues by autocatalysis, which activates kinase activity.
The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also designated Tyro3, Sky, Brt, Dtk, Etk2 and Tif), Axl (also designated UFO or ARK) and Mer (also designated Nyk or Eyk). Rse is expressed Preferentially in the adult brain with lower expression in other tissues. Axl is found at highest levels in heart and skeletal muscle. Mer has been identified as a tyrosine kinase is involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate , Lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S, have been identified as ligands for the UFO family of receptors.